Templates for designing and implementing clinical trials

 

Our goal is to develop a library of executable models for different kinds of randomised controlled trials which can be downloaded and populated with relevant data variables, decisions, workflows etc. OpenClinical.net will support users running these trials with databases and data mining services. It is anticipated that trials will be primarily trials of informatics interventions (e.g. to evaluate decision support or clinical pathway services) but it may be possible to use the services in traditional trials as well (e.g. to compare alternative treatments or other interventions where the trial model is published on Repertoire).

Template for traditional 2-arm RCT

First draft of a simple template for a randomised controlled trial

Template for multicellular RCT (Mosaic)

The cellular trial model offers the ability to carry out a mosaic of "mini-trials" during a single patient journey, either sequentially or concurrently.

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